Delta Sleep-Inducing Peptide (DSIP) is a naturally occurring short peptide, named for its ability to induce sleep in rabbits and first isolated in 1977 from rat brains during slow-wave sleep. Beyond its sleep-promoting effects, DSIP has several physiological and endocrine functions that are increasingly being explored. Current research indicates that DSIP can modulate corticotropin levels, inhibit somatostatin secretion, reduce stress, help normalize blood pressure, influence sleep patterns, and affect pain perception. Additionally, it holds potential for future applications in cancer therapy, depression management, and protection against free radical damage.
